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Ralf Weiskirchen Selected Research

Liver Cirrhosis (Hepatic Cirrhosis)

2/2024Soluble Semaphorin 4D Serum Concentrations Are Elevated in Critically Ill Patients with Liver Cirrhosis and Correlate with Aminotransferases.
11/2023Therapeutic potential of stem cells in regeneration of liver in chronic liver diseases: Current perspectives and future challenges.
1/2023Expression of Cyclin E1 in hepatic stellate cells is critical for the induction and progression of liver fibrosis and hepatocellular carcinoma in mice.
10/2022Glucagon-like peptide 1 and fibroblast growth factor-21 in non-alcoholic steatohepatitis: An experimental to clinical perspective.
12/2021Chronic mineral oil administration increases hepatic inflammation in wild type mice compared to lipocalin 2 null mice.
10/2021Physalin B attenuates liver fibrosis via suppressing LAP2α-HDAC1 mediated deacetylation of glioma-associated oncogene 1 and hepatic stellate cell activation.
4/2021It's all about the spaces between cells: role of extracellular matrix in liver fibrosis.
4/2021Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: mechanisms, treatment and prevention.
1/2021Liver Fibrosis-From Mechanisms of Injury to Modulation of Disease.
1/2021Fructose and Non-Alcoholic Steatohepatitis.
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Ralf Weiskirchen Research Topics

Disease

74Fibrosis (Cirrhosis)
03/2024 - 04/2002
64Liver Cirrhosis (Hepatic Cirrhosis)
02/2024 - 06/2002
50Inflammation (Inflammations)
03/2024 - 12/2003
30Neoplasms (Cancer)
03/2024 - 02/2003
23Liver Diseases (Liver Disease)
02/2024 - 06/2002
19Hepatocellular Carcinoma (Hepatoma)
02/2024 - 08/2009
19Critical Illness (Critically Ill)
02/2024 - 01/2010
18Non-alcoholic Fatty Liver Disease
02/2024 - 04/2010
18Sepsis (Septicemia)
02/2024 - 01/2010
12Obesity
12/2022 - 01/2010
10Infections
06/2023 - 12/2003
10Insulin Resistance
10/2022 - 05/2007
10Alcoholic Fatty Liver
10/2022 - 08/2014
10Hepatolenticular Degeneration (Wilson's Disease)
12/2021 - 08/2014
8Fatty Liver
05/2024 - 09/2010
7Chronic Hepatitis C
10/2011 - 12/2003
5Carcinogenesis
03/2024 - 07/2006
5Renal Insufficiency (Renal Failure)
12/2023 - 01/2013
5Type 2 Diabetes Mellitus (MODY)
12/2022 - 01/2010
5Cicatrix (Scar)
01/2020 - 04/2004
4Iron Overload
01/2024 - 01/2018
4Prostatic Neoplasms (Prostate Cancer)
06/2023 - 01/2018
4Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2021 - 01/2015
4Portal Hypertension
01/2021 - 05/2007
4Body Weight (Weight, Body)
01/2021 - 08/2009
4Cholestasis
01/2020 - 02/2015
4Hepatitis C
10/2015 - 04/2005
3Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
06/2024 - 01/2020
3Infertility (Sterility)
01/2024 - 06/2017
3Triple Negative Breast Neoplasms
01/2023 - 10/2020
3Virus Diseases (Viral Diseases)
01/2022 - 08/2005
3Ulcerative Colitis
01/2022 - 08/2020
3Pre-Eclampsia (Preeclampsia)
12/2020 - 01/2008
3Neoplasm Metastasis (Metastasis)
11/2020 - 01/2018
3Breast Neoplasms (Breast Cancer)
10/2020 - 01/2017
3Wounds and Injuries (Trauma)
07/2020 - 01/2013
3Liver Neoplasms (Liver Cancer)
01/2020 - 05/2010
3Disease Progression
01/2020 - 06/2010
3Acute-Phase Reaction
01/2019 - 05/2009
3Sarcoidosis (Schaumann Disease)
04/2015 - 06/2006

Drug/Important Bio-Agent (IBA)

35Proteins (Proteins, Gene)FDA Link
03/2024 - 02/2003
28Biomarkers (Surrogate Marker)IBA
02/2024 - 06/2007
23CytokinesIBA
05/2023 - 06/2002
18Lipocalin-2IBA
06/2023 - 02/2011
17Messenger RNA (mRNA)IBA
03/2024 - 06/2002
12IronIBA
06/2024 - 08/2004
12CollagenIBA
01/2023 - 10/2003
12Transforming Growth Factor beta (TGF-beta)IBA
01/2013 - 04/2002
9CopperIBA
11/2023 - 04/2015
9LipidsIBA
04/2023 - 09/2010
9Carbon Tetrachloride (Tetrachloromethane)IBA
01/2023 - 11/2010
7ChemokinesIBA
01/2019 - 06/2010
7Transforming Growth Factor beta1 (TGF beta 1)IBA
01/2013 - 06/2002
6Transforming Growth Factors (Transforming Growth Factor)IBA
03/2024 - 06/2002
6LigandsIBA
01/2021 - 08/2004
6EndoglinIBA
12/2020 - 05/2007
6Triglycerides (Triacylglycerol)IBA
01/2020 - 08/2014
5Collagen Type I (Type I Collagen)IBA
03/2024 - 05/2012
5CholesterolIBA
01/2024 - 01/2019
5AdipokinesIBA
12/2021 - 05/2007
5Acute-Phase Proteins (Acute-Phase Protein)IBA
12/2021 - 01/2010
5Chemokine ReceptorsIBA
04/2021 - 06/2010
5Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2019 - 12/2005
5Factor VII (Proconvertin)IBA
06/2014 - 03/2009
5Peptide Hydrolases (Proteases)FDA Link
06/2014 - 03/2009
4Glucose (Dextrose)FDA LinkGeneric
02/2024 - 05/2007
4FructoseIBA
02/2024 - 01/2017
4RNA (Ribonucleic Acid)IBA
02/2024 - 05/2005
4Perilipin-5IBA
02/2024 - 03/2019
4Insulin (Novolin)FDA Link
02/2024 - 11/2012
4InflammasomesIBA
05/2023 - 11/2012
4MicroRNAs (MicroRNA)IBA
03/2023 - 04/2013
4Vitamin A (Retinol)FDA LinkGeneric
01/2023 - 01/2007
4Fibronectins (Fibronectin)IBA
01/2023 - 01/2013
4Choline (Choline Chloride)IBA
12/2021 - 11/2010
4ZincIBA
04/2021 - 11/2012
4Retinol-Binding Proteins (Retinoid Binding Proteins)IBA
12/2019 - 05/2007
3Transaminases (Aminotransferases)IBA
02/2024 - 01/2020
3CyclinsIBA
01/2023 - 09/2012
3Liposomes (Liposome)IBA
01/2023 - 01/2018
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2022 - 05/2010
3Phosphatidylcholines (Phosphatidylcholine)IBA
01/2022 - 01/2021
3EnzymesIBA
01/2022 - 01/2008
3AntibodiesIBA
11/2021 - 01/2013
3Extracellular Matrix ProteinsIBA
04/2021 - 12/2010
3Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2020 - 10/2008
3Bile Acids and Salts (Bile Acids)IBA
01/2020 - 01/2018
3Hormones (Hormone)IBA
01/2020 - 06/2017
3AdiponectinIBA
12/2019 - 05/2007
3ResistinIBA
12/2019 - 05/2007
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 12/2005
3platelet-derived growth factor C (PDGF-C)IBA
01/2019 - 10/2008
3Hydroxyproline (4 Hydroxyproline)IBA
01/2019 - 03/2006
3Fetuin-BIBA
01/2019 - 04/2013
3Methionine (L-Methionine)FDA Link
08/2017 - 11/2010
3Connective Tissue Growth FactorIBA
05/2014 - 11/2007

Therapy/Procedure

24Therapeutics
06/2024 - 10/2013
9Ligation
01/2023 - 10/2003
6Liver Transplantation
12/2023 - 03/2009
6Laser Therapy (Surgery, Laser)
09/2020 - 08/2014